Syonell▼ (Valproate Semisodium) is licensed for the treatment of manic episodes in bipolar disorder when lithium is contraindicated or not tolerated
Syonell® ▼
(VALPROATE SEMISODIUM)
250mg & 500mg gastro-resistant tablets
Equivalent to 250mg
& 500mg Valproic Acid
Key Information
▼ This medicinal product is subject to additional monitoring
• Syonell is bioequivalent to the originator product, Depakote®.1
• Prescribing Syonell by brand reduces your drug spend.2
• Syonell is listed under Valproic Acid on formulary and GP databases.
• Prescribing Syonell by brand provides continuity of supply for the NHS and patients.
Refs: 1. Data on file LUP-VAL-02. 2. Data on file LUP-VAL-01.
Syonell ▼ (VALPROATE SEMISODIUM)
250mg Gastro-Resistant Tablets
| PIP Code | 4140760 |
| Product Licence Number | PL 35507/0191 |
| Lupin Product Code | 416225 |
| Product Classification | POM |
| Pack Size | 30 Tablets |
| List Price | £4.55 |
Syonell ▼ (VALPROATE SEMISODIUM)
500mg Gastro-Resistant Tablets
| PIP Code | 4140778 |
| Product Licence Number | PL 35507/0192 |
| Lupin Product Code | 416226 |
| Product Classification | POM |
| Pack Size | 30 Tablets |
| List Price | £9.10 |
Please be aware the following statement has been removed from the SmPC section 4.4
NICE has advised that generic switching of valproate preparations is not normally recommended due to the clinical implications of possible variations in plasma concentrations.
This is based on the fact that the NICE clinical guideline for Bipolar disorder: assessment and management [CG185] does not include any restrictions regarding switching between generics.
Syonell Cost Savings
• Prescribing Syonell® offers a saving of 20% over the NHS Drug Tariff price, based on the originator product. 1
| Brand | Strength | NHS List Price | Saving by prescribing Syonell® | Syonell® Discount |
|---|---|---|---|---|
| Depakote® | 250 mg 500 mg | £5.69 £11.37 | £1.14 £2.27 | 20% |
| Belvo® | 250 mg 500 mg | £5.69 £11.37 | £1.14 £2.27 | 20% |
| Drug Tariff | 250 mg 500 mg | £5.69 £11.37 | £1.14 £2.27 | 20% |
Syonell Supply Chain
At Lupin Healthcare we recognise the importance of continued supply of branded medicines and are committed to the highest quality standards. With this in mind we supply our products through all three mainline UK wholesalers.
▼ This medicinal product is subject to additional monitoring
Refs: 1. DATA ON FILE LUP-VAL-01
Downloads
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the leaflet. You can also report side effects directly by the Yellow Card Scheme website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
Contact Us
If you would like to know more about Syonell and the savings opportunity available or a detailed stock report please get in touch by email to: information@lupin.com or customer services on 01565 751378
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LUP-CORP-005s DOP: December 2020
LUP-CORP-005s DOP: December 2020
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