NaMuscla^®

In order to work normally, muscles need messages from the brain conducted via nerves. When a message from the brain reaches the muscles, microscopic channels in the muscle cell wall – called sodium and chloride ion channels – open or close to turn this message into a brief electrical signal. The electrical signal triggers the muscle to work (contract). Normally, each signal from the brain results in a single response from a muscle and when the signal ends, the muscle relaxes as shown below.

In NDM, changes in the sodium or chloride ion channels caused by a gene defect mean that, instead of a single signal, each message from the nerve results in repeated signals in the muscle cells. These repeated signals cause the muscles to remain tensed up as shown below and it can take much longer for them to relax. This can lead to difficulties in moving around and may even affect your balance.

NDM muscle working (contraction and relaxation)

NaMuscla stops the abnormal response of the ion channels, which reduces the repeated signals, and helps the muscle work more normally as shown below. Studies with NaMuscla have shown that it works in patients with NDM caused by both sodium and chloride ion channel defects.

NaMuscla helps your muscles to work more normally

unlockNDM – Lupin Healthcare have developed a disease awareness site specifically for NDM.
You can access this by clicking on the NDM logo below:

Muscular Dystrophy UK – www.musculardystrophyuk.org

NHS National Channelopathy Service – www.channelopathy.nhs.uk

NaMuscla
Patient information leaflet